Skip to main content

PubMed Central

PubMed Central is a free full-text archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health's National Library of Medicine (NIH/NLM).


rss RSS

209,787
RESULTS


Show sorted alphabetically

Show sorted alphabetically

SHOW DETAILS
up-solid down-solid
eye
Title
Date Published
Creator
PubMed Central
by Roncero, Carlos; Vega, Pablo; Martinez-Raga, Jose; Barral, Carmen; Basurte-Villamor, Ignacio; Rodriguez-Cintas, Laia; Mesias, Beatriz; Grau-Lopez, Lara; Casas, Miguel; Szerman, Nestor
texts

eye 5,060

favorite 1

comment 0

This article is from International Journal of Mental Health Systems , volume 8 . Abstract Background: Since provision of integrated services for patients with dual pathology or dual disorders (coexistence of an addictive disorder and other psychiatric disorders) constitutes an important challenge, this study compared the perceptions of health-care professionals with the existing, current state of specific resources for patients with dual pathology in Spain. Methods: Epidemiological,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158069
PubMed Central
by Foote, Christopher
texts

eye 3,023

favorite 0

comment 0

This article is from BMC Research Notes , volume 7 . Abstract Contributing reviewers: The editors of BMC Research Notes would like to thank all of our reviewers who have contributed to the journal in volume 6 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895785
PubMed Central
by Sandhu, Jaspal Singh; Gupta, Giniya; Shenoy, Shweta
texts

eye 84

favorite 0

comment 0

This article is from Asian Journal of Sports Medicine , volume 1 . Abstract Purpose: Accurate measurement or prediction of fat mass is useful in physiology, nutrition and clinical medicine. Most predictive equations currently used to assess percentage of body fat or fat mass, using simple anthropometric measurements were derived from people in western societies and they may not be appropriate for individuals with other genotypic and phenotypic characteristics. We developed equations to predict...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289169
PubMed Central
by Sirim, Demet; Widmann, Michael; Wagner, Florian; Pleiss, Jurgen
texts

eye 180

favorite 0

comment 0

This article is from BMC Structural Biology , volume 10 . Abstract Background: Cytochrome P450 monooxygenases (CYPs) form a vast and diverse family of highly variable sequences. They catalyze a wide variety of oxidative reactions and are therefore of great relevance in drug development and biotechnological applications. Despite their differences in sequence and substrate specificity, the structures of CYPs are highly similar. Although being in research focus for years, factors mediating...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224734
PubMed Central
texts

eye 1,954

favorite 1

comment 0

This article is from United European Gastroenterology Journal , volume 1 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070603
PubMed Central
texts

eye 391

favorite 0

comment 0

This article is from Virology Journal , volume 11 . Abstract : The editors of Virology Journal would like to thank all our reviewers who have contributed to the journal in Volume 10 (2013). The success of any scientific journal depends on an effective and strict peer review process and Virology Journal could not operate without your contribution. We are grateful to the large number of reviewers (1026 to be exact!), who have done a great job in not only lifting the quality of the journal’s...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898089
PubMed Central
by Harold, Simon
texts

eye 1,915

favorite 0

comment 0

This article is from BMC Plant Biology , volume 14 . Abstract Contributing reviewers: The editors of BMC Plant Biology would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897928
PubMed Central
by Navidghasemizad, Sahar; Takala, Timo M; Alatossava, Tapani; Saris, Per EJ
texts

eye 85

favorite 0

comment 0

This article is from Bioengineered , volume 4 . Abstract In this study the growth of genetically modified Lactobacillus casei LAB6, overexpressing proline iminopeptidase PepI and its capacity to increase free proline was investigated during ripening of Edam cheese. The strain successfully survived 12 weeks of ripening period in cheese. The food-grade plasmid pLEB604, carrying the pepI gene, was stable, and PepI enzyme was active in LAB6 cells isolated at different stages of the ripening...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937202
PubMed Central
texts

eye 885

favorite 0

comment 0

This article is from Annals of The Royal College of Surgeons of England , volume 94 . Abstract INTRODUCTION: The preliminary results of a pyrocarbon interpositional radiocarpal implant in a small cohort of patients were reviewed. As it is currently only a limited release product, we describe to potential users early complications and negative outcomes. METHODS: Patients were assessed using pain levels, ranges of motion, grip strength, type of and time to return to work as well as pre-operative...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954246
PubMed Central
by Jackson, Chandra L; Kawachi, Ichiro; Redline, Susan; Juon, Hee-Soon; Hu, Frank B
texts

eye 78

favorite 0

comment 0

This article is from BMC Public Health , volume 14 . Abstract Background: Although short sleep is associated with an increased risk of morbidity as well as mortality and has been shown to vary by industry of employment and occupation, little is known about the relationship between work and sleep among Asian Americans. Methods: Using a nationally representative sample of US adults (n = 125,610) in the National Health Interview Survey from 2004–2011, we estimated prevalence ratios for...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057824
PubMed Central
by Morawska, Magdalena
texts

eye 1,147

favorite 0

comment 0

This article is from BMC Family Practice , volume 15 . Abstract Contributing reviewers: The editors of BMC Family Practice would like to thank all of our reviewers who have contributed to the journal in Volume 14 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121002
PubMed Central
by Hauser, Thomas; Adam, Jennifer; Schulz, Henry
texts

eye 235

favorite 0

comment 0

This article is from Theoretical Biology & Medical Modelling , volume 11 . Abstract Background: The purpose of this study was the comparison of the calculated (MLSSC) and experimental power (MLSSE) in maximal lactate steady-state (MLSS) during cycling. Methods: 13 male subjects (24.2 ± 4.76 years, 72.9 ± 6.9 kg, 178.5 ± 5.9 cm, V˙O2max: 60.4 ± 8.6 ml min−1 kg−1, V˙Lamax: 0.9 ± 0.19 mmol l-1 s-1) performed a ramp-test for determining the V˙O2max and a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052616
PubMed Central
by Sands, Tim
texts

eye 137

favorite 0

comment 0

This article is from BMC Systems Biology , volume 7 . Abstract Contributing reviewers: The editors of BMC Systems Biology would like to thank all our reviewers who have contributed to the journal in Volume 6 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626622
PubMed Central
by Gall, Astrid; Kaye, Steve; Hue, Stephane; Bonsall, David; Rance, Richard; Baillie, Gregory J; Fidler, Sarah J; Weber, Jonathan N; McClure, Myra O; Kellam, Paul
texts

eye 54

favorite 0

comment 0

This article is from Retrovirology , volume 10 . Abstract Background: Dynamic changes in Human Immunodeficiency Virus 1 (HIV-1) sequence diversity and divergence are associated with immune control during primary infection and progression to AIDS. Consensus sequencing or single genome amplification sequencing of the HIV-1 envelope (env) gene, in particular the variable (V) regions, is used as a marker for HIV-1 genome diversity, but population diversity is only minimally, or semi-quantitatively...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605130
PubMed Central
texts

eye 77

favorite 0

comment 0

This article is from BMC Systems Biology , volume 8 . Abstract Background: Living cells are realized by complex gene expression programs that are moderated by regulatory proteins called transcription factors (TFs). The TFs control the differential expression of target genes in the context of transcriptional regulatory networks (TRNs), either individually or in groups. Deciphering the mechanisms of how the TFs control the expression of target genes is a challenging task, especially when multiple...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080427
PubMed Central
by Rehman Malik, Abdur; Iqbal Quddusi, Ahmed; Naila,
texts

eye 163

favorite 0

comment 0

This article is from Pakistan Journal of Medical Sciences , volume 29 . Abstract Objective: The study was conducted to determine the etiology of seizures in neonates.Methods: This was a descriptive Cross-sectional study. This study was conducted at neonatal unit of children hospital and institute of child health Multan from June 2012 to April 2013. A total of 285 neonates who presented with seizures were enrolled for the possible causes. First line investigations including blood glucose, serum...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858915
PubMed Central
texts

eye 1,278

favorite 1

comment 0

This article is from United European Gastroenterology Journal , volume 1 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070608
PubMed Central
by Sands, Timothy R
texts

eye 749

favorite 0

comment 0

This article is from BMC Systems Biology , volume 8 . Abstract Contributing reviewers: The editors of BMC Systems Biology would like to thank all our reviewers who have contributed to the journal in Volume 7 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914848
PubMed Central
texts

eye 79

favorite 0

comment 0

This article is from Current Neuropharmacology , volume 10 . Abstract Obsessive-compulsive disorder (OCD) is rarely associated with schizophrenia, whereas 20 to 30% of schizophrenic patients, suffer from comorbid obsessive-compulsive symptoms (OCS). So far no single pathogenetic theory convincingly explained this fact suggesting heterogeneous subgroups. Based on long-term case observations, one hypothesis assumes that second-onset OCS in the course of schizophrenia might be a side effect of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286851
PubMed Central
by Hommel, Marcel
texts

eye 1,315

favorite 0

comment 0

This article is from Malaria Journal , volume 13 . Abstract Contributing reviewers: Malaria Journal would like to thank all reviewers who have contributed to the journal in 2013.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917501
PubMed Central
by Solera, Dafne
texts

eye 2,537

favorite 0

comment 0

This article is from BMC Cancer , volume 14 . Abstract Contributing reviewers: The editors of BMC Cancer would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909450
PubMed Central
texts

eye 198

favorite 0

comment 0

This article is from Bioinformatics , volume 28 . Abstract Summary: GenAlEx: Genetic Analysis in Excel is a cross-platform package for population genetic analyses that runs within Microsoft Excel. GenAlEx offers analysis of diploid codominant, haploid and binary genetic loci and DNA sequences. Both frequency-based (F-statistics, heterozygosity, HWE, population assignment, relatedness) and distance-based (AMOVA, PCoA, Mantel tests, multivariate spatial autocorrelation) analyses are provided. New...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463245
PubMed Central
texts

eye 176

favorite 0

comment 0

This article is from ZooKeys . Abstract AbstractThe first overview on the Auchenorrhyncha fauna of peat bogs of the Austrian Bohemian Forest is presented. Seven oligotrophic peat bog sites were studied in 2011 by suction sampler (“G-Vac”) and 93 Auchenorrhyncha species (with 7465 adult specimens) were recorded. Eleven species (about 18 % of the individuals) are tyrphobiontic or tyrphophilous. The relative species abundance plot is not very steep; the six most abundant species represent...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764520
PubMed Central
by Richards, Ashley M.; Von Dwingelo, Juanita E.; Price, Christopher T.; Abu Kwaik, Yousef
texts

eye 81

favorite 0

comment 0

This article is from Virulence , volume 4 . Abstract Legionella pneumophila is an aquatic organism that interacts with amoebae and ciliated protozoa as the natural hosts, and this interaction plays a central role in bacterial ecology and infectivity. Upon transmission to humans, L. pneumophila infect and replicate within alveolar macrophages causing pneumonia. Intracellular proliferation of L. pneumophila within the two evolutionarily distant hosts is facilitated by bacterial exploitation of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710333
PubMed Central
by Greene, Michael W.; Burrington, Christine M.; Lynch, Darin T.; Davenport, Samantha K.; Johnson, Andrew K.; Horsman, Melissa J.; Chowdhry, Saleem; Zhang, Jian; Sparks, Janet D.; Tirrell, Paul C.
texts

eye 101

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Steatosis, oxidative stress, and apoptosis underlie the development of nonalcoholic steatohepatitis (NASH). Protein kinase C delta (PKCδ) has been implicated in fatty liver disease and is activated in the methionine and choline-deficient (MCD) diet model of NASH, yet its pathophysiological importance towards steatohepatitis progression is uncertain. We therefore addressed the role of PKCδ in the development of steatosis, inflammation,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893275
PubMed Central
texts

eye 91

favorite 0

comment 0

This article is from Genome Announcements , volume 2 . Abstract Streptococcus iniae ISET0901 is a virulent strain isolated in 2007 from diseased tilapia. Its full genome is 2,070,856 bp. The availability of this genome will allow comparative genomics to identify virulence genes important for the pathogenesis of streptococcosis caused by S. iniae, as well as possible immunogens for vaccine development.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047457
PubMed Central
by Pan, Li; Hu, Jia-Liang; Wang, Wen-Jing; Zhang, Xiao-Juan; Wei, Jin; Liu, Zhen-Dong; Zhang, Yi-Hua; Xu, Han-Mei
texts

eye 73

favorite 0

comment 0

This article is from International Journal of Molecular Sciences , volume 13 . Abstract (R,R)ZX-5 is a NO regulatory compound, which could significantly increase choroidal blood flow in New Zealand rabbit. The aim of this paper is to investigate the molecular mechanism of (R,R)ZX-5 promoting NO production. Besides this, we also investigated the antiangiogenic activity of (R,R)ZX-5. Analysis of Western blot showed that (R,R)ZX-5 up-regulated the expression of Akt, p-Akt (Thr473), eNOS and p-eNOS...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317683
PubMed Central
by Morawska, Magdalena
texts

eye 1,235

favorite 0

comment 0

This article is from BMC Oral Health , volume 14 . Abstract Contributing reviewers: The editors of BMC Oral Health would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921989
PubMed Central
by Rondeau, Gaelle; Abedinpour, Parisa; Desai, Prerak; Baron, Veronique T.; Borgstrom, Per; Welsh, John
texts

eye 103

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract In metastasis, circulating tumor cells penetrate the walls of blood vessels and enter the metastatic target tissue, thereby becoming exposed to novel and relatively unsupportive microenvironments. In the new microenvironments, the tumor cells often remain in a dormant state indefinitely and must adapt before they are able to successfully colonize the tissue. Very little is known about this adaptive process. We studied temporal changes in gene...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086928
PubMed Central
by Schluter, Jan-Philip; Reinkensmeier, Jan; Barnett, Melanie J; Lang, Claus; Krol, Elizaveta; Giegerich, Robert; Long, Sharon R; Becker, Anke
texts

eye 187

favorite 0

comment 0

This article is from BMC Genomics , volume 14 . Abstract Background: Sinorhizobium meliloti is a soil-dwelling α-proteobacterium that possesses a large, tripartite genome and engages in a nitrogen fixing symbiosis with its plant hosts. Although much is known about this important model organism, global characterization of genetic regulatory circuits has been hampered by a lack of information about transcription and promoters. Results: Using an RNAseq approach and RNA populations representing 16...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616915
PubMed Central
by Pafitis, Natalie
texts

eye 2,297

favorite 0

comment 0

This article is from BMC Public Health , volume 13 . Abstract Contributing reviewers: The editors of BMC Public Health would like to thank all our reviewers who have contributed to the journal in 2012.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751667
PubMed Central
texts

eye 182

favorite 0

comment 0

This article is from Therapeutics and Clinical Risk Management , volume 10 . Abstract Lymphangioleiomyomatosis (LAM) is an uncommon disease presented as diffuse thin-walled cystic changes in the lung. The main differential diagnoses include pulmonary Langerhans’ histiocytosis (PLCH), Birt-Hogg-Dubé syndrome (BHD), lymphoid interstitial pneumonia (LIP), and amyloidosis. A combination of clinical, radiological, and pathological approaches as well as genetic testing will clarify the diagnosis...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149398
PubMed Central
by Morawska, Magdalena
texts

eye 1,484

favorite 0

comment 0

This article is from BMC Gastroenterology , volume 14 . Abstract Contributing reviewers: The editors of BMC Gastroenterology would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898228
PubMed Central
by Padmanabhan, Roshan; Lagier, Jean-Christophe; Dangui, Nicole Prisca Makaya; Michelle, Caroline; Couderc, Carine; Raoult, Didier; Fournier, Pierre-Edouard
texts

eye 72

favorite 0

comment 0

This article is from Standards in Genomic Sciences , volume 8 . Abstract Megasphaera massiliensis strain NP3T sp. nov. is the type strain of Megasphaera massiliensis sp. nov., a new species within the genus Megasphaera. This strain, whose genome is described here, was isolated from the fecal flora of an HIV-infected patient. M. massiliensis is a Gram-negative, obligate anaerobic coccobacillus. Here we describe the features of this organism, together with the complete genome sequence and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910696
PubMed Central
by Waldmann, Jost; Gerken, Jan; Hankeln, Wolfgang; Schweer, Timmy; Glockner, Frank Oliver
texts

eye 248

favorite 0

comment 0

This article is from BMC Research Notes , volume 7 . Abstract Background: Advances in sequencing technologies challenge the efficient importing and validation of FASTA formatted sequence data which is still a prerequisite for most bioinformatic tools and pipelines. Comparative analysis of commonly used Bio*-frameworks (BioPerl, BioJava and Biopython) shows that their scalability and accuracy is hampered. Findings: FastaValidator represents a platform-independent, standardized, light-weight...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094456
PubMed Central
by Roshier, David A; Heinsohn, Robert; Adcock, Gregory J; Beerli, Peter; Joseph, Leo
texts

eye 53

favorite 0

comment 0

This article is from Ecology and Evolution , volume 2 . Abstract There are many large, easy-to-observe anseriform birds (ducks, geese, and swans) in northern Australia and New Guinea and they often gather in large numbers. Yet, the structure of their populations and their regional movements are poorly understood. Lack of understanding of population structure limits our capacity to understand source-sink dynamics relevant to their conservation or assess risks associated with avian-borne...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501632
PubMed Central
by Velasco-Castrillon, Alejandro; Schultz, Mark B.; Colombo, Federica; Gibson, John A. E.; Davies, Kerrie A.; Austin, Andrew D.; Stevens, Mark I.
texts

eye 55

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Terrestrial life in Antarctica has been described as some of the simplest on the planet, and mainly confined to soil microfaunal communities. Studies have suggested that the lack of diversity is due to extreme environmental conditions and thought to be driven by abiotic factors. In this study we investigated soil microfauna composition, abundance, and distribution in East Antarctica, and assessed correlations with soil geochemistry and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909186
PubMed Central
by Gungor, Burcin; Gombos, Imre; Crul, Tim; Ayaydin, Ferhan; Szabo, Laszlo; Torok, Zsolt; Mates, Lajos; Vigh, Laszlo; Horvath, Ibolya
texts

eye 107

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Eukaryotic cells exhibit a characteristic response to hyperthermic treatment, involving morphological and cytoskeletal alterations and the induction of heat shock protein synthesis. Small GTPases of the Ras superfamily are known to serve as molecular switches which mediate responses to extracellular stimuli. We addressed here how small GTPase Rac1 integrates signals from heat stress and simultaneously induces various cellular changes in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930703
This article is from GMS Zeitschrift für Medizinische Ausbildung , volume 31 . Abstract The practice of assessing student performance in human, dental and veterinary medicine at universities in German-speaking countries has undergone significant changes in the past decade. Turning the focus to practical requirements regarding medical practice during undergraduate study away from an often theory-dominated curriculum, the academic scrutiny of the basics of teaching medical knowledge and skills,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152998
PubMed Central
by Zhou, Ting; Lu, Saihua; Liu, Xiufeng; Zhang, Ye; Xu, Feng
texts

eye 184

favorite 0

comment 0

This article is from Patient preference and adherence , volume 7 . Abstract Human serum albumin (HSA) is an ideal natural colloid that has been widely used in clinical practice for supplemental albumin or as a plasma substitute during therapeutic plasma exchanges to redress hypoproteinemia. However, a paucity of well-designed clinical trials, a lack of a clear cut survival benefit, and frequent case reports of adverse drug reaction (ADR) make the use of HSA controversial. This study aims to...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849079
PubMed Central
by Al-Halabi, Becher; Marwan, Yousef; Hasan, Mohammad; Alkhadhari, Sulaiman
texts

eye 59

favorite 0

comment 0

This article is from Advances in Medical Education and Practice , volume 5 . Abstract Background: Research is the foundation of scientific advancement and improvement in quality of health care, which ensures the good health of the community. The aim of this study is to explore experiences, attitudes, and barriers of medical students in Kuwait University (KU) in regards to extracurricular research. Methods: A questionnaire about extracurricular research activities (ie, any research activity that...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010614
PubMed Central
by Golshiri, Ali; Mokhtaree, Mohammad Reza; Shabani, Ziba; Tabatabaee, Sayed Taghi; Rahnama, Amir; Moradi, Mohammad; Sayadi, Ahamad Reza; Faezi, Hadi
texts

eye 74

favorite 0

comment 0

This article is from Addiction & Health , volume 1 . Abstract Background:: To determine the effect of opium smoking cessation on the frequency and type of microorganisms in the nasopharynx of opium smokers. Methods:: This was a cross-sectional study performed in psychology and ENT department of Moradi Hospital of Rafsanjan University of Medical Sciences in 2008 (Kerman, Iran). Nasopharyngeal cultures were taken from 50 opium smokers before and 2 to 3 months after cessation of opium smoking....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905491
PubMed Central
texts

eye 199

favorite 0

comment 0

This article is from Bioinformatics , volume 30 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058949
PubMed Central
by Klopfleisch, Robert; Meyer, Anja; Schlieben, Patricia; Bondzio, Angelika; Weise, Chris; Lenze, Dido; Hummel, Michael; Einspanier, Ralf; Gruber, Achim D
texts

eye 102

favorite 0

comment 0

This article is from BMC Veterinary Research , volume 8 . Abstract Background: Canine mast cell tumour proliferation depends to a large extent on the activity of KIT, a tyrosine kinase receptor. Inhibitors of the KIT tyrosine kinase have recently been introduced and successfully applied as a therapeutic agent for this tumour type. However, little is known on the downstream target genes of this signaling pathway and molecular changes after inhibition. Results: Transcriptome analysis of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489685
PubMed Central
by Hoffman, Donald D.; Prakash, Chetan
texts

eye 122

favorite 2

comment 0

This article is from Frontiers in Psychology , volume 5 . Abstract Current models of visual perception typically assume that human vision estimates true properties of physical objects, properties that exist even if unperceived. However, recent studies of perceptual evolution, using evolutionary games and genetic algorithms, reveal that natural selection often drives true perceptions to extinction when they compete with perceptions tuned to fitness rather than truth: Perception guides adaptive...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060643
PubMed Central
by Tabata, Ryo; Sawa, Shinichiro
texts

eye 132

favorite 0

comment 0

This article is from Frontiers in Plant Science , volume 5 . Abstract In the past decade, small secreted peptides have proven to be essential for various aspects of plant growth and development, including the maintenance of certain stem cell populations. Most small secreted peptides identified in plants to date are recognized by membrane-localized receptor kinases, the largest family of receptor proteins in the plant genome. This peptide-receptor interaction is essential for initiating...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082320
PubMed Central
by Chae, Hyeseon; Min, Kyungdoo; Youn, kanwoo; Park, Jinwoo; Kim, Kyungran; Kim, Hyocher; Lee, Kyungsuk
texts

eye 90

favorite 0

comment 0

This article is from Annals of Occupational and Environmental Medicine , volume 26 . Abstract Objectives: This study estimated the rate of agricultural injury using a nationwide survey and identified factors associated with these injuries. Methods: The first Korean Farmers’ Occupational Disease and Injury Survey (KFODIS) was conducted by the Rural Development Administration in 2009. Data from 9,630 adults were collected through a household survey about agricultural injuries suffered in 2008....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012551
PubMed Central
by Decaro, Nicola; Martella, Vito; Desario, Costantina; Lanave, Gianvito; Circella, Elena; Cavalli, Alessandra; Elia, Gabriella; Camero, Michele; Buonavoglia, Canio
texts

eye 95

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Dog circovirus (DogCV) was identified in an outbreak of enteritis in pups in Italy. The disease was observed in 6 young dachshunds pups of a litter from a breeding kennel and caused the death of 2 dogs. Upon full-genome analysis, the virus detected in one of the dead pups (strain Bari/411–13) was closely related to DogCVs that have been recently isolated in the USA. The present study, if corroborated by further reports, could represent a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141843
PubMed Central
by Lossius, Hans Morten; S?reide, Kjetil; Bache, Kristi G
texts

eye 876

favorite 0

comment 0

This article is from Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine , volume 22 . Abstract Contributing reviewers: The Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine—which received its first Impact Factor in 2013—is extremely grateful for the time, hard work and support of its highly-qualified peer reviewers. The editors of the Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, the Norwegian Air Ambulance Foundation and BioMed...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973829
PubMed Central
by Nikeghbalian, S.; Aliakbarian, M.; Kazemi, K.; Shamsaeefar, A. R.; Mehdi, S. H.; Bahreini, A.; Malek-Hosseini, S. A.
texts

eye 62

favorite 0

comment 0

This article is from International Journal of Organ Transplantation Medicine , volume 5 . Abstract Background: Tumors involving the root of the mesentery are generally regarded as “unresectable” with conventional surgical techniques. Resection with conventional surgery may end in life-threatening complications in these patients. Ex-vivo resection and auto-transplantation avoids excessive bleeding and prevents ischemic related damage to the small intestine and other organs. Objective: To...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149739
PubMed Central
by Rendleman, Justin; Antipin, Yevgeniy; Reva, Boris; Adaniel, Christina; Przybylo, Jennifer A.; Dutra-Clarke, Ana; Hansen, Nichole; Heguy, Adriana; Huberman, Kety; Borsu, Laetitia; Paltiel, Ora; Ben-Yehuda, Dina; Brown, Jennifer R.; Freedman, Arnold S.; Sander, Chris; Zelenetz, Andrew; Klein, Robert J.; Shao, Yongzhao; Lacher, Mortimer; Vijai, Joseph; Offit, Kenneth; Kirchhoff, Tomas
texts

eye 73

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Molecular and genetic evidence suggests that DNA repair pathways may contribute to lymphoma susceptibility. Several studies have examined the association of DNA repair genes with lymphoma risk, but the findings from these reports have been inconsistent. Here we provide the results of a focused analysis of genetic variation in DNA repair genes and their association with the risk of non-Hodgkin's lymphoma (NHL). With a population of 1,297 NHL...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092067
PubMed Central
by Nagaraj, Anil Kumar Mysore
texts

eye 1,056

favorite 1

comment 0

This article is from Indian Journal of Psychiatry , volume 55 . Abstract Sex is a mysterious phenomenon, which has puzzled even great sages. Human beings have researched and mastered the biology of sex. But that is not all. Sex needs to be understood from the spiritual perspective too. The vision of Osho is an enlightening experience in this regard. Out of the thousands of lectures, five lectures on sex made Osho most notorious. Born into a Jain family of Madhya Pradesh, Rajneesh, who later...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705694
PubMed Central
by Baveewo, Steven; Kamya, Moses R; Mayanja-Kizza, Harriet; Fatch, Robin; Bangsberg, David R; Coates, Thomas; Hahn, Judith A; Wanyenze, Rhoda K
texts

eye 97

favorite 0

comment 0

This article is from BMC Research Notes , volume 5 . Abstract Background: Rapid HIV tests provide same-day results and are widely used in HIV testing programs in areas with limited personnel and laboratory infrastructure. The Uganda Ministry of Health currently recommends the serial rapid testing algorithm with Determine, STAT-PAK, and Uni-Gold for diagnosis of HIV infection. Using this algorithm, individuals who test positive on Determine, negative to STAT-PAK and positive to Uni-Gold are...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392728
PubMed Central
by Linhart, Radek; Wong, Sarah Anne; Cao, Jieyun; Tran, Melody; Huynh, Anne; Ardrey, Casey; Park, Jong Min; Hsu, Christine; Taha, Saher; Peterson, Rentia; Shea, Shannon; Kurian, Jason; Venderova, Katerina
texts

eye 95

favorite 0

comment 0

This article is from Molecular Neurodegeneration , volume 9 . Abstract Background: Parkinson’s disease (PD) is the most common movement neurodegenerative movement disorder. An incomplete understanding of the molecular pathways involved in its pathogenesis impedes the development of effective disease-modifying treatments. To address this gap, we have previously generated a Drosophila model of PD that overexpresses PD pathogenic mutant form of the second most common causative gene of PD,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126812
This article is from BMJ Open , volume 2 . Abstract Objectives: To apply sociological theories to understand public trust in extended services provided by community pharmacists relative to those provided by general practitioners (GPs). Design: Qualitative study involving focus groups with members of the public. Setting: The West of Scotland. Participants: 26 purposively sampled members of the public were involved in one of five focus groups. The groups were composed to represent known groups of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358628
PubMed Central
texts

eye 43

favorite 0

comment 0

This article is from Nanoscale Research Letters , volume 9 . Abstract The electrochemical growth of Co nanowires in ultra-high aspect ratio InP membranes has been investigated by fast Fourier transform-impedance spectroscopy (FFT-IS) in the frequency range from 75 Hz to 18.5 kHz. The impedance data could be fitted very well using an electric circuit equivalent model with a series resistance connected in series to a simple resistor-capacitor (RC) element and a Maxwell element. Based on the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094693
PubMed Central
by Wellbrock, Jasmin; Sheikhzadeh, Sara; Oliveira-Ferrer, Leticia; Stamm, Hauke; Hillebrand, Mathias; Keyser, Britta; Klokow, Marianne; Vohwinkel, Gabi; Bonk, Veronika; Otto, Benjamin; Streichert, Thomas; Balabanov, Stefan; Hagel, Christian; Rybczynski, Meike; Bentzien, Frank; Bokemeyer, Carsten; von Kodolitsch, Yskert; Fiedler, Walter
texts

eye 322

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Backgrounds: The Loeys-Dietz syndrome (LDS) is an inherited connective tissue disorder caused by mutations in the transforming growth factor β (TGF-β) receptors TGFBR1 or TGFBR2. Most patients with LDS develop severe aortic aneurysms resulting in early need of surgical intervention. In order to gain further insight into the pathophysiology of the disorder, we investigated circulating outgrowth endothelial cells (OEC) from the peripheral...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130545
PubMed Central
by Andersson, Ulrika; Wibom, Carl; Cederquist, Kristina; Aradottir, Steina; Borg, Ake; Armstrong, Georgina N.; Shete, Sanjay; Lau, Ching C.; Bainbridge, Matthew N.; Claus, Elizabeth B.; Barnholtz-Sloan, Jill; Smith, Marcel; Eze, Ogechukwu; Way, Mahalia; Lada, Pat; Miedzianowski, Nancy; Frechette, Michelle; Paleologos, Nina; Bystrom, Gudrun; Svedberg, Eva; Huggert, Sara; Lai, Rose; Kimdal, Mikael; Sandstrom, Monica; Brannstrom, Nikolina; Hayat, Amina; Tihan, Tarik; Zheng, Shichun; Berger, Mitchel;...
texts

eye 182

favorite 0

comment 0

This article is from Neuro-Oncology , volume 16 . Abstract Background: Although familial susceptibility to glioma is known, the genetic basis for this susceptibility remains unidentified in the majority of glioma-specific families. An alternative approach to identifying such genes is to examine cancer pedigrees, which include glioma as one of several cancer phenotypes, to determine whether common chromosomal modifications might account for the familial aggregation of glioma and other cancers....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165415
PubMed Central
by Jerosch-Herold, Christina; Shepstone, Lee; Wilson, Edward CF; Dyer, Tony; Blake, Julian
texts

eye 95

favorite 0

comment 0

This article is from BMC Musculoskeletal Disorders , volume 15 . Abstract Background: Carpal tunnel syndrome (CTS) is the most common neuropathy of the upper limb and a significant contributor to hand functional impairment and disability. Effective treatment options include conservative and surgical interventions, however it is not possible at present to predict the outcome of treatment. The primary aim of this study is to identify which baseline clinical factors predict a good outcome from...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921988
PubMed Central
by Tami-Maury, Irene; Coulibaly, Yaya Ibrahim; Cissoko, Souare Salimata; Dao, Sounkalo; Kristensen, Sibylle
texts

eye 77

favorite 0

comment 0

This article is from The Pan African Medical Journal , volume 11 . Abstract Introduction: In 2004, the sudden availability of free antiretroviral therapy (ART in Mali, within the context of an already overburdened health care system created gaps in individual patient quality of care. The objective of this study was to determine the prevalence of HIV-related oral manifestations (OM) during the first month of ART therapy in a Malian health facility. Methods: Medical records of adult patients who...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283017
PubMed Central
by Kus-Liskiewicz, Malgorzata; Polanska, Joanna; Korfanty, Joanna; Olbryt, Magdalena; Vydra, Natalia; Toma, Agnieszka; Widlak, Wieslawa
texts

eye 126

favorite 0

comment 0

This article is from BMC Genomics , volume 14 . Abstract Background: Elevated temperatures induce activation of the heat shock transcription factor 1 (HSF1) which in somatic cells leads to heat shock proteins synthesis and cytoprotection. However, in the male germ cells (spermatocytes) caspase-3 dependent apoptosis is induced upon HSF1 activation and spermatogenic cells are actively eliminated. Results: To elucidate a mechanism of such diverse HSF1 activity we carried out genome-wide...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711851
PubMed Central
by Baumard, Josselin; Osiurak, Francois; Lesourd, Mathieu; Le Gall, Didier
texts

eye 89

favorite 0

comment 0

This article is from Frontiers in Psychology , volume 5 . Abstract In this paper we review studies that investigated tool use disorders in left-brain damaged (LBD) patients over the last 30 years. Four tasks are classically used in the field of apraxia: Pantomime of tool use, single tool use, real tool use and mechanical problem solving. Our aim was to address two issues, namely, (1) the role of mechanical knowledge in real tool use and (2) the cognitive mechanisms underlying pantomime of tool...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033127
PubMed Central
texts

eye 117

favorite 0

comment 0

This article is from Biodiversity Data Journal . Abstract AbstractAn annotated English translation of a German early 19th century text including Latin diagnoses is presented with a high-quality scan of the original publication and direct links to the cited pages with taxon and literature citations (including TL-2 entries).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031435
PubMed Central
by Mustafa, Norlaila; Kamarudin, Nor Azmi; Ismail, Ab Aziz; Khir, Amir Sharifuddin; Ismail, Ikram Shah; Musa, Kamarul Imran; Kadir, Khalid Abdul; Yaacob, Nor Azwany; Ali, Osman; Isa, Siti Harnida Md; Wan Bebakar, Wan Mohamad; wan Mohamud, Wan Nazaimoon
texts

eye 150

favorite 0

comment 0

This article is from Diabetes Care , volume 34 . Abstract OBJECTIVE: To determine the prevalence of prediabetes and diabetes among rural and urban Malaysians. RESEARCH DESIGN AND METHODS: This cross-sectional survey was conducted among 3,879 Malaysian adults (1,335 men and 2,544 women). All subjects underwent the 75-g oral glucose tolerance test (OGTT). RESULTS: The overall prevalence of prediabetes was 22.1% (30.2% in men and 69.8% in women). Isolated impaired fasting glucose (IFG) and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114358
PubMed Central
by Shipley, Tim
texts

eye 1,028

favorite 0

comment 0

This article is from BMC Neurology , volume 14 . Abstract Contributing reviewers: The editors of BMC Neurology would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973960
PubMed Central
by Ribeiro, Daniela O; Pinto, Daniela C; Lima, Luis Mauricio TR; Volpato, Nadia M; Cabral, Lucio M; de Sousa, Valeria P
texts

eye 74

favorite 0

comment 0

This article is from Nutrition Journal , volume 10 . Abstract Background: The objective of this work was to study the vitamins B1, B2, B6 and C stability in a pediatric formulation containing high amounts of calcium in the presence of organic phosphate, amino acids, glucose, sodium chloride, magnesium sulfate, pediatric vitamins and trace elements under different conditions using developed and validated analytical methods. Methods: The study was carried out during 72 h with formulations...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115844
This article is from Nucleic Acids Research , volume 39 . Abstract Tgs1 is the enzyme that converts m7G RNA caps to the 2,2,7-trimethylguanosine (TMG) caps characteristic of spliceosomal snRNAs. Fungi grow vegetatively without TMG caps, thereby raising the question of what cellular transactions, if any, are TMG cap-dependent. Here, we report that Saccharomyces cerevisiae Tgs1 methyltransferase activity is essential for meiosis. tgs1Δ cells are specifically defective in splicing PCH2 and SAE3...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141232
PubMed Central
by Park, Sungha; Lakatta, Edward G.
texts

eye 53

favorite 0

comment 0

This article is from Yonsei Medical Journal , volume 53 . Abstract Increased arterial stiffness is an independent predictor of cardiovascular disease independent from blood pressure. Recent studies have shed new light on the importance of inflammation on the pathogenesis of arterial stiffness. Arterial stiffness is associated with the increased activity of angiotensin II, which results in increased NADPH oxidase activity, reduced NO bioavailability and increased production of reactive oxygen...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282971
PubMed Central
by Jensen, Britt W; Nichols, Melanie; Allender, Steven; de Silva-Sanigorski, Andrea; Millar, Lynne; Kremer, Peter; Lacy, Kathleen; Swinburn, Boyd
texts

eye 69

favorite 0

comment 0

This article is from BMC Public Health , volume 12 . Abstract Background: Intake of sweet drinks has previously been associated with the development of overweight and obesity among children and adolescents. The present study aimed to assess the consumption pattern of sweet drinks in a population of children and adolescents in Victoria, Australia. Methods: Data on 1,604 children and adolescents (4–18 years) from the comparison groups of two quasi-experimental intervention studies from...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549827
PubMed Central
by Wiessing, Lucas; Ferri, Marica; Grady, Bart; Kantzanou, Maria; Sperle, Ida; Cullen, Katelyn J.; Hatzakis, Angelos; Prins, Maria; Vickerman, Peter; Lazarus, Jeffrey V.; Hope, Vivian D.; Mathei, Catharina
texts

eye 125

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Background: People who inject drugs (PWID) are a key population affected by hepatitis C virus (HCV). Treatment options are improving and may enhance prevention; however access for PWID may be poor. The availability in the literature of information on seven main topic areas (incidence, chronicity, genotypes, HIV co-infection, diagnosis and treatment uptake, and burden of disease) to guide HCV treatment and prevention scale-up for PWID in the 27...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113410
This article is from PLoS ONE , volume 9 . Abstract Understanding the primary effects of anthropogenic activities and natural factors on river water quality is important in the study and efficient management of water resources. In this study, analysis of Variance (ANOVA), Principal component analysis (PCA), Pearson correlations, Multiple regression analysis (MRA) and Redundancy analysis (RDA) were applied as an integrated approach in a GIS environment to explore the temporal and spatial...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121078
PubMed Central
by Wagner, Gerd; Koch, Kathrin; Schachtzabel, Claudia; Schultz, C. Christoph; Gaser, Christian; Reichenbach, Jurgen R.; Sauer, Heinrich; Bar, Karl-Jurgen; Schlosser, Ralf G.
texts

eye 55

favorite 0

comment 0

This article is from NeuroImage : Clinical , volume 3 . Abstract Several lines of evidence suggest that cognitive control deficits may be regarded as a connecting link between reported impairments in different cognitive domains of schizophrenia. However, the precise interplay within the fronto-cingulo-thalamic network known to be involved in cognitive control processes and its structural correlates has only been sparsely investigated in schizophrenia. The present multimodal study was therefore...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791293
PubMed Central
by Marcora, Maria S; Fernandez-Gamba, Agata C; Avendano, Luz A; Rotondaro, Cecilia; Podhajcer, Osvaldo L; Vidal, Ruben; Morelli, Laura; Ceriani, Maria F; Castano, Eduardo M
texts

eye 51

favorite 0

comment 0

This article is from Molecular Neurodegeneration , volume 9 . Abstract Background: Familial British and Familial Danish dementias (FBD and FDD, respectively) are associated with mutations in the BRI2 gene. Processing of the mutated BRI2 protein leads to the accumulation in the brain of the 34-mer amyloid Bri (ABri) and amyloid Dan (ADan) peptides, accompanied by neurofibrillary tangles. Recently, transgenic mice successfully reproduced different aspects of FDD, while modeling of FBD in vivo has...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898387
This article is from Philosophy, Ethics, and Humanities in Medicine : PEHM , volume 9 . Abstract Introduction: In his classic essay “The phenomenological approach to psychopathology”, Karl Jaspers defended the irreducible reality of the “subjective” mental symptoms and stressed the pivotal role of empathy in their diagnostic assessment. However, Jaspers’ account of the epistemological role of empathy in psychopathological diagnosis was far from clear: whereas at several places Jaspers...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995426
PubMed Central
by Wuestenberg, Andrea; Kah, Janine; Singethan, Katrin; Sirma, Huseyin; Keller, Amelie Dorothea; Rosal, Sergio Rene Perez; Schrader, Jorg; Loscher, Christine; Volz, Tassilo; Bartenschlager, Ralf; Lohmann, Volker; Protzer, Ulrike; Dandri, Maura; Lohse, Ansgar W.; Tiegs, Gisa; Sass, Gabriele
texts

eye 201

favorite 0

comment 0

This article is from PLoS ONE , volume 9 . Abstract Background & Aims: HMG-CoA-reductase-inhibitors (statins) have been shown to interfere with HCV replication in vitro. We investigated the mechanism, requirements and contribution of heme oxygenase-1(HO-1)-induction by statins to interference with HCV replication. Methods: HO-1-induction by fluva-, simva-, rosuva-, atorva- or pravastatin was correlated to HCV replication, using non-infectious replicon systems as well as the infectious cell...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011762