1. Get and install DOSBox.
2.Download the the 7Z zip file.
3. Unzip it.(I use "7-Zip File Manager"
4. extract the .bin file using "7-Zip File Manager"
"7-Zip File Manager" doesn't just extract .7Z zip files, it also extracts .zip files as well, but it didn't say whether or not this .bin file was extracted as a .7Z file or a .zip file which is weird, but worked for me.

5. Make sure there is a shortcut of DOSBox you have in sight to use
6. then drag the file called SIERRA.EXE into the DOSBox shortcut and the game will run

To save, just go to the top right of the screen that is that funny looking volume bottom, then click "save", then click "Change Directory", then click "OK" or tap enter on the keyboard, then type in the name you want the save to be called(not the file path to where it is be save to, wink wink), then save.

From here you can just drag and drop the file called SIERRA.EXE into DOSBox when ever you want to play King's Quest V,
however if you want or need to change different settings with DOSBox it will help to use a custom DOSBox config for games and such:
Now, if you don't already know how to make custom config files for dosbox you should learn how.

I will try to give you an outline for that.

For my basic path in Windows, it is:
C:\Users\username\AppData\Local\DOSBox

the username is the username of your Windows account.

In that folder there should be a DOSBox config file which I recommend copying into a folder or you desktop,
then rename it something like KingsQuest5_WithVoices.conf,
open the file and scroll down to the bottom of it and leave it open

now open a Command Prompt in Windows and drag and drop the folder that King's Quest resides in into it, copy that folder path by holding down shift then hold down the arrow key to highlight it, then Ctrl-C to copy,

then paste that into the end of the custom DOSBox config file called KingsQuest5_WithVoices.conf with Ctrl-V,

You can name the folder that holds King's Quest V what ever you want, but simplicity sake let's name it Kings Quest 5, so that the numbers appear in the right order if it was in a deeper folder:
Now make it look something like this:
MOUNT C "C:\Users\username\Desktop\Kings Quest 5"
C:
SIERRA.EXE

but of coarse instead of the file path I have here it will be the file path you copied.

Now that the DOSBox config file named KingsQuest5_WithVoices.conf is created, drag and drop that into this folder path:
C:\Users\username\AppData\Local\DOSBox

in a text file change this command according to the paths you are using:
"C:\Program Files (x86)\DOSBox-0.74-3\DOSBox.exe" -conf "C:\Users\username\AppData\Local\DOSBox\KingsQuest5_WithVoices.conf"
The next step is to create a shortcut by right clicking and creating a shortcut. and use the custom command you just modified there,

Then when DOSBox.exe pops up after that replace it with the name you want. Spaces aren't a problem here. I for instance named my shortcut as:
Kings Quest 5 With Voices

Now go and study up on how to use the config file to change settings for this game and so on.

This proccess was nearly the same for me in Ubuntu Linux. One difference is that in Bash command it is Ctrl-shift-C for copy and Ctrl-shift-V for paste, but in text files it is Ctrl-C for copy and Ctrl-V for paste. The paths will be different also. Good luck!