mapDamage: tracking and quantifying damage patterns in ancient DNA sequences
mapDamage




bioconda
installation
conda install -c bioconda mapdamage2=2.2.1
- python3 version 2.2.1 with R and 4 mandatory packages for the Bayesian inference:
conda install -c bioconda mapdamage2=2.2.1=pyr40_0
Important
- From version
2.2.1
the master
branch is requiring python3 as python2
is not supported from 2020-01-01.
Introduction
Complete documentation, instructions, examples, screenshots and FAQ are available at this address.
mapDamage2 is a computational framework written in Python3 and R, which tracks and quantifies DNA damage patternsamong ancient DNA sequencing reads generated by Next-Generation Sequencing platforms.
mapDamage
was developed at the Centre for GeoGenetics by the Orlando Group .
Citation
If you use this program, please cite the following publication:Jónsson H, Ginolhac A, Schubert M, Johnson P, Orlando L.mapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters.Bioinformatics 23rd April 2013. doi: 10.1093/bioinformatics/btt193
The original mapDamage1
was published in the following article:Ginolhac A, Rasmussen M, Gilbert MT, Willerslev E, Orlando L.mapDamage: testing for damage patterns in ancient DNA sequences. Bioinformatics 2011 27(15):2153-5http://bioinformatics.oxfordjournals.org/content/27/15/2153
Test the no-stats part and rescaling
you can test mapDamage
by running:
cd mapDamage/mapdamage/python3 mp_test.py
should return
```Started with the command: /usr/local/bin/mapDamage -i tests/test.bam -r tests/fake1.fasta -d tests/results --no-stats Reading from 'tests/test.bam' Writing results to 'tests/results/'pdf tests/results/Fragmisincorporationplot.pdf generatedadditional tests/results/Lengthplot.pdf generatedSuccessful run
.
Ran 2 tests in 3.357s
OK```
Contact
Please report bugs and suggest possible improvements on GitHub:https://github.com/ginolhac/mapDamage/issues/new
To restore the repository download the bundle
wget https://archive.org/download/github.com-ginolhac-mapDamage_-_2021-06-23_07-29-35/ginolhac-mapDamage_-_2021-06-23_07-29-35.bundle
and run:
git clone ginolhac-mapDamage_-_2021-06-23_07-29-35.bundle
Source:
https://github.com/ginolhac/mapDamageUploader:
ginolhacUpload date: 2021-06-23